Table 1.
Baseline characteristics of the study cohort by systolic blood pressure category.
| Systolic blood pressure category (mm Hg) | ||||||
|---|---|---|---|---|---|---|
| <110 | 110-119 | 120-139 | 140-159 | ≥160 | ||
| Total | n | 4,389 | 9,381 | 53,931 | 58,719 | 17,983 |
| Women | n | 2,186 (50) | 4,686 (50) | 28,250 (52) | 34,453 (59) | 12,252 (68) |
| Age | Mean, SD | 88.0 (5.4) | 87.1 (5.4) | 85.8 (5.2) | 85.1 (4.9) | 85.6 (4.9) |
| Frailty | Fit | 957 (22) | 2,192 (23) | 15,197 (28) | 21,129 (36) | 7,519 (42) |
| Mild | 1,658 (38) | 3,680 (39) | 22,017 (41) | 23,581 (40) | 6,821 (38) | |
| Moderate | 1,244 (28) | 2,479 (26) | 12,369 (23) | 10,843 (18) | 2,850 (16) | |
| Severe | 530 (12) | 1,030 (11) | 4,348 (8) | 3,166 (5) | 793 (4) | |
| Comorbidity at entry | CHD | 1,555 (35) | 3,332 (36) | 15,890 (29) | 12,870 (22) | 3,253 (18) |
| Stroke | 545 (12) | 1,180 (13) | 5,637 (10) | 4,465 (8) | 1,236 (7) | |
| Cancer | 964 (22) | 2,044 (22) | 11,045 (20) | 11,264 (19) | 3,108 (17) | |
| COPD | 1,040 (24) | 2,022 (22) | 11,142 (21) | 10,789 (18) | 2,932 (16) | |
| Musculoskeletal | 2,988 (68) | 6,527 (70) | 39,093 (72) | 42,096 (72) | 12,208 (68) | |
| Digestive | 2,592 (59) | 5,477 (58) | 31,240 (58) | 32,200 (55) | 8,823 (49) | |
| Nervous system | 3,077 (70) | 6,650 (71) | 39,057 (72) | 41,781 (71) | 12,103 (67) | |
| Dementia | 710 (16) | 1,342 (14) | 4,500 (8) | 2,377 (4) | 516 (3) | |
| Total Cholesterol (mmol/L) | Mean, SD, | 4.4 (1.1) | 4.5 (1.2) | 4.8 (1.2) | 5.1 (1.2) | 5.4 (1.2) |
| Diastolic Blood Pressure (mm Hg) | Mean, SD, | 63 (10) | 69 (10) | 74 (10) | 79 (10) | 84 (12) |
| Smoking status | Non smoker | 1,340 (31) | 3,445 (37) | 22,759 (42) | 27,304 (47) | 8,211 (46) |
| Current smoker | 517 (12) | 1,351 (14) | 8,359 (16) | 8,624 (15) | 2,189 (12) | |
| Ex smoker | 732 (17) | 1,904 (20) | 12,030 (22) | 12,522 (21) | 3,281 (18) | |
| Not recorded | 1,800 (41) | 2,681 (29) | 10,783 (20) | 10,269 (17) | 4,302 (24) | |
| Antihypertensive medications* | 2,141 (49) | 4,898 (52) | 31,912 (59) | 37,258 (63) | 11,264 (63) | |
| Renin angiotensin system medicatiions † | 1,476 (69) | 3,064 (63) | 17,136 (54) | 18,297 (49) | 5,531 (49) | |
| Beta-blockers † | 676 (32) | 1,745(36) | 10,764 (34) | 12,578 (34) | 4,308 (38) | |
| Calcium channel blockers † | 482 (23) | 1,425 (29) | 12,633 (40) | 16,091 (43) | 4,704 (42) | |
| Diuretics † | 332 (16) | 1,021 (21) | 10,502 (33) | 17,320 (46) | 5,943 (53) | |
| Other antihypertensive † | 86 (4) | 287 (6) | 2,591 (8) | 4,075 (11) | 1,701 (15) | |
Figures are frequencies (column percent) except where indicated.
*
drugs prescribed in first 12 months of patients’ record
†
as percent of participants treated with antihypertensive drugs