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. 2017 Jun 15;13(6):e1006407. doi: 10.1371/journal.ppat.1006407

Fig 4. Cross-sectional and orthogonal confocal images of mixed-species biofilms.

Fig 4

(A) S.m-C.a WT, (B) S.m-C.a pmt4ΔΔ, and (C) S.m-C.a och1ΔΔ. (A1-C1) Top view of biofilms, (A2-C2) magnified images of representative areas, (A3-C3) orthogonal views of biofilms, and (A4-C4) orthogonal views of EPS glucan-matrix. S.m-C.a WT biofilm displays numerous hyphal (mostly located in the outer layer; see white arrows) and yeast form of C. albicans with abundant amount of bacteria and densely-packed EPS glucans. In contrast, S.m-C.a pmt4ΔΔ and S.m-C.a och1ΔΔ display only a few of C. albicans with significant reduction of bacterial cells and disruption of the matrix.