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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: J Trauma Acute Care Surg. 2017 Feb;82(2):302–308. doi: 10.1097/TA.0000000000001313

TABLE 2.

Univariate Analysis & Multiple Logistic Regression of Coagulation Factors

Univariate Analysis
Multiple Logistic Regression
n OR CI (95%) p OR CI (95%) p
Factorsa
 II, (% activity) 939 0.76 (0.70–0.83) <0.001
 V, (% activity) 953 0.77 (0.71–0.83) <0.001 0.86 (0.76–0.97) 0.02
 VII, (% activity) 913 0.99 (0.95–1.04) 0.77
 VIII, (% activity) 964 0.98 (0.97–0.99) 0.001 0.97 (0.95–0.99) 0.007
 IX, (% activity) 935 0.89 (0.86–0.93) <0.001
 X, (% activity) 938 0.75 (0.70–0.81) <0.001 0.79 (0.68–0.92) 0.002
Protein C a, (% activity) 963 0.94 (0.89–0.99) 0.02 1.17 (1.05–1.30) 0.005
TBI 1,426 10.92 (7.81–15.27) <0.001 17.00 (8.78–32.92) <0.001
Blunt Injury 1,424 2.75 (2.02–3.73) <0.001 0.43 (0.21–0.87) 0.02
Age (Years) 1,427 1.04 (1.03–1.04) <0.001 1.04 (1.03–1.06) <0.001
Base Excess, (mEq/L) 1,023 0.94 (0.92–0.97) <0.001 0.90 (0.86–0.94) <0.001
n = 631
AUC = 0.89
a

Per 10 unit change

OR, Odds Ratio; CI (95%), Confidence Interval (95%); TBI, Traumatic Brain Injury