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. Author manuscript; available in PMC: 2018 May 18.
Published in final edited form as: Cell Chem Biol. 2017 Apr 13;24(5):565–575.e4. doi: 10.1016/j.chembiol.2017.03.013

Figure 6. Cisplatin analogs reversed cyanide induced changes in oxidative metabolism in rabbits.

Figure 6

A representative rabbit injected with cyanide demonstrating A) increased concentration of hemoglobin in the oxygenated state (red) compared to the deoxygenated state (blue) in the CNS and B) decreased cytochrome oxidase c redox ratio in the muscle (black). Injection of 36 (C-D) or 3 (E-F) after the cyanide infusion results in rapid reversal of cyanide induced pathophysiologic changes. n=5.