Fig 1. Scheme of this study.
#: Samples were drawn at end of treatment (EOT) for most of the cases other than two cases that suffered from viral breakthrough (VBT). Abbreviations: IFN, interferon; DAAs, direct-acting anti-viral agents; D/A; daclatasvir and asuneprevir; S/L: sofosbuvir and ledipasvir; HCC, hepatocellular carcinoma; Pre, pre-treatment; EOT, end of treatment, PBMC, peripheral blood mononuclear cells; SMV, simeprevir; PEG, pegylated, RBV, ribavirin;.