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. 2017 Jun 8;11:1707–1717. doi: 10.2147/DDDT.S133344

Table 1.

Correlation coefficient and release rate constants of CIM, IBU, and NAP from PLGA microcapsules after fitting to the various release rate equations

Drug Correlation coefficient (r2) Rate constant/n value

Higuchi Korsmeyer–Peppas Higuchi, K (h−1) Korsmeyer–Peppas, n value
CIM 0.6919 0.9879 19.715 0.81
IBU 0.9889 0.9836 11.947 0.41
NAP 0.9474 0.9191 7.472 0.44

Abbreviations: CIM, cimetidine; IBU, ibuprofen; NAP, naproxen; PLGA, poly(d,l-lactide-co-glycolide).