Figure 6. BG1 and PG9 interactions with V1V2.
(A) BG1 interactions with N-linked glycans attached to Asn156gp120 and Asn160gp120 shown for BG1_A (left) and BG1_B (right). (B) PG9 interactions with N-linked glycans attached to Asn156gp120 and Asn160gp120 from PG9-Env cryo-EM structure reported here (left) and from the crystal structure of PG9-V1V2 scaffold (PDB 3U4E) (right). The position of the CDRH3 loop in the PG9-Env cryo-EM structure is shown by a dashed line representing the position of CDRH3 in the PG9-V1V2 scaffold structure.