Table 1.
Provincial cost estimates and probabilities
| Variable | Ontario | British Columbia | Quebec |
|---|---|---|---|
| Cost estimates | |||
|
| |||
| Cystoscopy (± 25%) | $394 ($295, $492) | $362 ($271, $452)a | $330 ($247, $412) |
| WLC-assisted TURBT (± 25%) | $3946 ($2959, $4933) | $3002 ($2252, $3753)a | $2059 ($1544, $2573) |
| BLC-assisted TURBT (± 25%) | $4890 ($3667, $6113) | $3930 ($2947, $4913) | $2990 ($2242, $3737) |
| CT scan (± 25%) | $263 ($197, $329) | $650 ($487, $812) | $400 ($300, $500) |
| Cystectomy (± 25%) | $24 486 ($18 364, $30 608) | $21 190 ($15 892, $26,487)a | $17 894 ($13 420, $22 367) |
| Palliative care (± 25%) | $55 215 ($41 411, $69,018) | $55 215 ($41 411, $69 018) | $55 215 ($41 411, $69 018) |
| Perioperative mitomycin intravesical therapy (± 25%) | $754 ($565, $943) | $739 ($554, $924)a | $725 ($543, $906) |
| BCG intravesical therapy** (± 25%) | $204 ($153, $256) | $134 ($100, $168)a | $64 ($48, $80) |
| BLC-extra nursing time (± 25%) | $25 ($18, $31) | $9 ($7, $11) | $10 ($7, $12) |
| BLC-extra staffing cost (± 25%) | $15 ($11, $18) | $9 ($7, $11) | $12 ($9, $15)b |
| BLC-consumables (± 25%) | $708 ($531, $885) | $712 ($534, $891) | $712 ($534, $891) |
| BLC-additional equipment (± 25%) | $195 ($146, $244) | $195 ($146, $244) | $195 ($146, $244) |
| WLC sensitivity (95% CI) | 0.65 (0.55–0.74) | 0.65 (0.55–0.74) | 0.65 (0.55–0.74) |
| BLC sensitivity (95% CI) | 0.93 (0.90–0.96) | 0.93 (0.90–0.96) | 0.93 (0.90–0.96) |
| *RR, BLC vs. WLC (95% CI) | 0.761 (0.627–0.924) | 0.761 (0.627–0.924) | 0.761 (0.627–0.924) |
|
| |||
| Probabilities*** | |||
|
| |||
| 3-month recurrence, low-risk | 0.02 | ||
| 3-month recurrence, int-risk | 0.04 | ||
| 3-month recurrence, high-risk | 0.094 | ||
| 12-month recurrence, low-risk | 0.15 | ||
| 12-month recurrence, int-risk | 0.26 | ||
| 12-month recurrence, high-risk | 0.39 | ||
| 2-year recurrence, low-risk | 0.10 | ||
| 2-year recurrence, int-risk | 0.13 | ||
| 2-year recurrence, high-risk | 0.11 | ||
| 3-year recurrence, low-risk | 0.05 | ||
| 3-year recurrence, int-risk | 0.06 | ||
| 3-year recurrence, high-risk | 0.06 | ||
| 4-year recurrence, low-risk | 0.08 | ||
| 4-year recurrence, int-risk | 0.05 | ||
| 4-year recurrence, high-risk | 0.02 | ||
| 5-year recurrence, low-risk | 0.07 | ||
| 5-year recurrence, int-risk | 0.03 | ||
| 5-year recurrence, high-risk | 0.03 | ||
a
Average of Ontario and Quebec values;
b
average of Ontario and British Columbia values;
*
relative risk for recurrence;23
**
cost per weekly instillation;
BCG: bacillus Calmette-Guerin; BLC: blue light cystoscopy; CI: confidence interval; CT: computed tomography; PDD: photodynamic diagnosis; RR: relative risk; TURBT: transurethral resection of bladder tumour; WLC: white light cystoscopy.