Table 3.
Odds ratios for associations of clinical and behavioral variables with CPDD (n= 50,314)*
| Characteristic | Univariate OR |
95% CI | Multivariate OR |
95% CI |
|---|---|---|---|---|
| Tobacco Use (ever) | 0.62 | 0.60, 0.64 | 0.73 | 0.70, 0.76 |
| Alcohol Abuse | 0.55 | 0.53, 0 .58 | 0.62 | 0.58, 0.65 |
| BMI Underweight (<18.5) | 0.75 | 0.66, 0.85 | 0.84 | 0.73, 0.96 |
| Normal (18.5–24.99) | Referent | Referent | ||
| Overweight (25–29.99) | 1.16 | 1.11,1.22 | 1.08 | 1.03, 1.14 |
| Obese (30–39.99) | 1.12 | 1.07, 1.17 | 1.04 | 0.99, 1.1 |
| Morbidly Obese ≥40 | 0.88 | 0.81, 0.96 | 0.87 | 0.79, 0.96 |
| Coronary Artery Disease | 0.68 | 0.66, 0.71 | 0.76 | 0.73, 0.79 |
| Congestive Heart Failure | 0.65 | 0.62, 0.67 | 0.71 | 0.67, 0.75 |
| Diabetes mellitus | 0.76 | 0.73, 0.79 | 0.79 | 0.76, 0.83 |
| Chronic Kidney Disease | 1.08 | 1.04, 1.13 | 1.12 | 1,07, 1.18 |
| Hypertension | 0.7 | 0.67, 0.74 | 0.77 | 0.72, 0.82 |
| Osteoarthritis | 2.17 | 2.08, 2.26 | 2.26 | 2.15, 2.37 |
| Gout | 2.55 | 2.44, 2.66 | 2.82 | 2.69, 2.95 |
| Rheumatoid Arthritis | 2.07 | 1.93, 2.23 | 1.88 | 1.74, 2.03 |
| Hemochromatosis | 1.92 | 1.62, 2.26 | 1.87 | 1.57, 2.24 |
| Osteoporosis | 1.25 | 1.18, 1.33 | 1.26 | 1.16, 1.36 |
| Hyperparathyroidism | 2.96 | 2.64, 3.3 | 3.35 | 2.96, 3.79 |
| Hypothyroidism | 0.9 | 0.86, 0.95 | 0.88 | 0.83, 0.92 |
| Hypomagnesemia | 1.04 | 0.98, 1.11 | 1.28 | 1.19, 1.36 |
*
All characteristics, comorbidities, medications and arthroplasties listed in Table 2 were covariates in the multivariate analysis; age and sex were matched prior to analysis and not included in models.