Table 4.
Odds ratios for associations with therapies in CPDD vs controls (n= 50,314)
| Characteristic | Univariate OR |
95% CI | Multivariate OR |
95% CI |
|---|---|---|---|---|
| Medication | ||||
| Bisphosphonate | 1.10 | 1.03, 1.17 | 0.85 | 0.78, 0.93 |
| Calcium | 1.17 | 1.10, 1.25 | 1.15 | 1.06, 1.24 |
| Diuretic- Loop | 0.72 | 0.69, 0.75 | 0.80 | 0.76, 0.84 |
| Diuretic- Thiazide | 0.81 | 0.78, 0.84 | 0.84 | 0.81, 0.88 |
| Proton Pump Inhibitor | 0.59 | 0.57, 0.61 | 0.58 | 0.55, 0.60 |
| Joint Arthroplasty | ||||
| Knee | 1.94 | 1.82, 2.07 | 1.64 | 1.53, 1.76 |
| Hip | 1.31 | 1.20, 1.42 | 1.02 | 0.93, 1.12 |
| Shoulder | 1.53 | 1.27, 1.83 | 1.22 | 1.0004, 1.48 |
*
All characteristics, comorbidities, medications and arthroplasties listed in Table 2 were covariates in the multivariate analysis; age and sex were matched prior to analysis and not included in models.