Table 2.
Comparison of PCOS women with both biochemical and clinical hyperandrogenism versus PCOS women isolated clinical hyperandrogenism.
| Parameters | Clinical and biochemical hyperandrogenism n = 58 | Clinical hyperandrogenism n = 52 | P-value |
|---|---|---|---|
| Salivary Testosterone (pmol/L) | 81.69 (357.11) | 16.76 (8.21) | <0.001 |
| BMI (kg/m2) | 35.94 (7.44) | 31.76 (7.55) | <0.001 |
| Waist Circumference (cm) | 103.76 (17.23) | 96.57 (15.46) | 0.035 |
| Hip Circumference (cm) | 121.57 (16.25) | 113.05 (16.96) | 0.036 |
| Baseline Glucose (mmol/L) | 4.96 (1.33) | 4.74 (0.54) | 0.329 |
| 2 Hour Glucose (mmol/L) | 6.46 (2.60) | 5.53 (1.28) | 0.187 |
| Insulin (μIU/ml) | 20.92 (17.72) | 11.65 (6.86) | <0.001 |
| HOMA-IR | 5.30 (7.97) | 2.53 (1.73) | <0.001 |
Values in (mean (SD)). HOMA-IR – homeostatic model assessment – insulin resistance. BMI – Body Mass Index. Comparison of PCOS women with both biochemical and clinical hyperandrogenism (raised serum T and/or a raised FAI) compared to those PCOS women with clinical hyperandrogenism (no elevated serum androgen level). As shown in this analysis, PCOS women with both biochemical and clinical hyperandrogenism showed a more metabolic phenotype compared to those PCOS women with clinical hyperandrogenism alone.