FIGURE 4.

Effects of UA on the levels of inflammatory cytokines: TNF-a, IL-6, and IL-1β. HaCaT cells were treated with UA at 0, 10, and 15 μM 16 h before exposure to 20 Gy gamma radiation. DMEM group without any drug treatment and gamma radiation exposure served as control. The levels of TNF-α (A), IL-6 (B), and IL-1β (C) in cell lysate were evaluated using ELISA. All data were expressed as mean ± SEM. Comparisons between groups were analyzed by One-Way ANOVA followed by Tukey’s post hoc test. ^∗p < 0.05 vs. non-irradiated. #p < 0.05 vs. irradiated and no drug treatment.