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. 2017 Jun 12;8:15616. doi: 10.1038/ncomms15616

Figure 7. INO80 translocates along DNA at the H2A–H2B dimer interface to displace DNA and promote H2A.Z exchange.

Figure 7

A model showing DNA translocation by INO80 close to the DNA entry site of nucleosomes for nucleosome mobilization and histone dimer exchange. Translocation persistently destabilizes dimer–DNA interactions and promotes the exchange of H2A.Z–H2B dimer.