TABLE 2.
Genea | Gene product | Mutationb | Presence of mutation in strain |
||||
---|---|---|---|---|---|---|---|
Daughter's |
Mother's |
||||||
Father's JJ2546 (urine) | JJ2547 (kidney drainage) | JJ2548 (blood) | JJ2963 (urine) | JJ2974 (feces) | |||
P423_00080 | Arylsulfatase | G32A (G11D) | + | + | |||
degS | Peptidase RseP (regulator of sigma E) | C259A (H87N) | + | ||||
ykgC | Pyridine nucleotide-disulfide oxidoreductase | A445G (T149A) | + | + | |||
nfsB | Dihydropteridine reductase | G73T (E25stop) | + | ||||
ybdK | Gamma-glutamyl:cysteine ligase | G759A (M253I) | + | ||||
cspE | Cold shock protein CspE (RNA chaperone) | G157T (E53stop) | + | ||||
lipA | Lipoyl synthase | T683C (I228T) | + | + | |||
dps | Stationary-phase protection protein Dps | G127T (intergenic) | + | ||||
ycgJ | Hypothetical protein | C121T (intergenic) | + | ||||
dnaC | DNA replication protein DnaC (phage) | C333A (SYN) | + | + | |||
ydbH | Hypothetical protein YdbH | G1937A (W646stop) | + | + | |||
yebC | Putative transcriptional regulator | C239T (A80V) | + | + | |||
yfaL | Autotransporter | C1431T (SYN) | + | ||||
lrhA | Transcriptional regulator LrhA | A41_T42ins 6 bp (D14_L15ins LD) | + | ||||
P423_12990 | Peptidase S10 | C476T (P159L) | + | ||||
fadJ | Fatty acid oxidation protein subunit alpha | G1863A (SYN) | + | ||||
P423_13360 | Membrane protein | T129A (SYN) | + | + | |||
crr | PTS glucose transporter subunit IIA (EIIA_Glc) | A260T (E87V) | + | ||||
fhlA | Sigma 54-dependent transcriptional regulator | G878A (W293stop) | + | + | |||
sdaC | Serine/threonine transporter | A25G (I9V) | + | ||||
mltA | Murein transglycosylase A | C206T (S69L) | + | ||||
P423_16465 | 9-O-Acetyl-N-acetylneuraminic acid deacetylase | A351C (L117F) | + | ||||
P423_16480 | N-Acetylneuraminic acid mutarotase | T407C (I136T) | + | + | |||
P423_16705 | Polysialic acid transporter | C44T (intergenic) | + | + | |||
rapZ | GlmZ (sRNA)-inactivating NTPase | C1486T (N188S) | + | + | |||
malT | Transcriptional regulator | A1004C (E335A) | + | ||||
ftsY | Signal recognition particle-docking protein | C1486T (R496stop) | + | + | |||
P423_19450 | Oligopeptidase A | A303G (SYN) | + | ||||
cspA | Cold shock protein upstream CspA | C74A (intergenic) | + | ||||
glyS | Glycyl-tRNA synthetase (subunit B) | C1933T (R645C) | + | ||||
gltS | Sodium/glutamate symport carrier protein GltS | C848T (L283P) | + | ||||
frvA | Fructose-specific PTS (EIIA_Frc) | C371T (A124V) | + | + | |||
ilvN | Acetolactate synthase | A35C (E12A) | + | + | |||
rbsR | Transcriptional regulator RbsR | G748T (V253F) | + | ||||
P423_21035 | Arylsulfatase | C1292T (T431I) | + | + | |||
P423_21850 | Hypothetical protein | T765G (I255M) | + | + | + | ||
ntrC | Sigma 54-dependent transcriptional regulator | G817A (A273T) | + | + | |||
bsmA | Biofilm stress and motility protein BsmA | A133G (I45V) | + | ||||
P423_24355 | Restriction endonuclease | C1223T (P408L) | + |
Gene number or name as in reference JJ1886 genome (NCBI accession number NC_022648). For those genes without a designated name in the JJ1886 annotation, the homolog designation available from annotations of other E. coli strains was used. Genes encoding transcriptional regulators are shown in bold.
The position of an intergenic mutation is shown as the distance from a start codon of the gene. Amino acid changes are given in parentheses.
SYN, synonymous; ins, insertion; PTS, phosphotransferase system; +, mutation is present.