Table 2.
Odds ratios (ORs) and 95% confidence intervals (CIs) for hypertension in relation to HDL-cholesterol stratified by circulating CD34-positive cell levels
| HDL-cholesterol tertiles | p for trend | 1 SD increment of HDL (13.8 mg/dL) | |||
|---|---|---|---|---|---|
| T1 (low) | T2 | T3 (high) | |||
| Total subjects | |||||
| No. of participants | 161 | 155 | 161 | ||
| No. of cases (%) | 101 (62.7) | 98 (63.2) | 99 (61.5) | ||
| Age-adjusted ORs | 1.00 | 1.02 (0.64, 1.61) | 0.96 (0.61, 1.51) | 0.860 | 1.05 (0.87, 1.27) |
| Age- and BMI-adjusted ORs | 1.00 | 1.08 (0.67, 1.72) | 1.22 (0.76, 1.96) | 0.415 | 1.19 (0.97, 1.45) |
| Multivariable ORs | 1.00 | 1.06 (0.66, 1.72) | 1.09 (0.66, 1.79) | 0.737 | 1.13 (0.92, 1.40) |
| High CD34-positive cell (≥0.99 cells/μL) | |||||
| No. of participants | 89 | 78 | 73 | ||
| No. of cases (%) | 53 (59.6) | 52 (66.7) | 51 (69.9) | ||
| Age-adjusted ORs | 1.00 | 1.31 (0.69, 2.48) | 1.63 (0.84, 3.16) | 0.142 | 1.24 (0.95, 1.62) |
| Age- and BMI-adjusted ORs | 1.00 | 1.43 (0.75, 2.75) | 2.12 (1.05, 4.27) | 0.035 | 1.40 (1.05, 1.86) |
| Multivariable ORs | 1.00 | 1.48 (0.76, 2.88) | 2.34 (1.11, 4.91) | 0.025 | 1.44 (1.06, 1.96) |
| Low CD34-positive cell (<0.99 cells/μL) | |||||
| No. of participants | 72 | 77 | 88 | ||
| No. of cases (%) | 48 (66.7) | 46 (59.7) | 48 (54.5) | ||
| Age-adjusted ORs | 1.00 | 0.77 (0.39, 1.51) | 0.60 (0.31, 1.15) | 0.123 | 0.89 (0.68, 1.17) |
| Age- and BMI-adjusted ORs | 1.00 | 0.76 (0.38, 1.51) | 0.72 (0.37, 1.41) | 0.345 | 1.00 (0.75, 1.33) |
| Multivariable ORs | 1.00 | 0.69 (0.33, 1.44) | 0.50 (0.24, 1.05) | 0.068 | 0.87 (0.63, 1.19) |
Hypertension is defined as systolic blood pressure ≥140 mmHg, and/or diastolic blood pressure ≥90 mmHg, and/or antihypertensive medication use. Multivariable ORs: adjusted further for age and BMI, smoking status, alcohol consumption, HbA1C, LDL, AST, γ-GTP, UA and GFR. HDL tertiles are <51 mg/dL for T1, 51–61 mg/dL for T2, and >61 mg/dL for T3