Table 1.
Univariate analysis of slowly and rapidly growing nontuberculous mycobacterial infections among 64 patients in Seobuk hospital, South Korea
| Variable | SGM (n = 33) | RGM (n = 31) | p-value |
|---|---|---|---|
| Species | M.avium complex 29 | M.abscessus complex 27 | |
| M.avium 13 | M.fortuitum complex 4 | ||
| M.intracellulare 16 | |||
| M.kansasii 4 | |||
| Age (years), Mean ± SD | 65.5 ± 15.5 | 61.7 ± 15.9 | NS |
| Sex, n (%) | NS | ||
| Male | 21 (63.6) | 16 (51.6) | |
| Female | 12 (36.4) | 15 (48.4) | |
| Chest X-ray, n (%) | NS | ||
| Bronchiectasis | 13 (39.4) | 14 (45.2) | |
| Cavity | 11 (33.3) | 16 (51.6) | |
| Destroyed lung | 6 (18.2) | 6 (19.4) | |
| Nodule | 18 (54.5) | 15 (48.4) | |
| Infiltration | 27 (81.8) | 24 (77.4) | |
| Fibrosis | 27 (81.8) | 18 (58.1) | |
| Smoking, n (%) | 7 (21.2) | 8 (25.8) | NS |
| Alcoholic consumption, n (%) | 4 (12.1) | 8 (25.8) | NS |
| History of pulmonary tuberculosis, n (%) | 23 (69.7) | 26 (83.9) | NS |
| History of recurrent tuberculosis, n (%) | 5 (15.2) | 14 (45.2) | NS |
| History of multi-drug resistant tuberculosis, n (%) | 3 (9.1) | 6 (19.4) | NS |
| Current tuberculosis, n (%) | 1 (3.0) | 9 (29.0) | .041 |
| Symptom screening, n (%) | |||
| Chronic Fatigue | 26 (78.8) | 23 (74.2) | NS |
| Cough | 31 (93.9) | 30 (96.8) | <.05 |
| Sputum | 29 (87.9) | 29 (93.5) | .011 |
| Hemoptysis | 8 (24.2) | 10 (32.3) | NS |
| Dyspnea on exertion | 11 (33.3) | 9 (29.0) | NS |
| Fever | 2 (6.1) | 4 (12.9) | NS |
| Chest pain | 3 (9.1) | 4 (12.9) | NS |
| Weight (kg), Mean ± SD | 49.1 ± 7.1 | 52.6 ± 13.5 | NS |
| Hemoglobin (g/dL), Mean ± SD | 12.2 ± 1.2 | 12.4 ± 2.0 | NS |
| WBC (/mm3), Mean ± SD | 6967.7 ± 2043.6 | 6867.9 ± 2463.3 | NS |
| Protein (g/dL), Mean ± SD | 7.2 ± 0.7 | 7.0 ± 0.8 | NS |
| Albumin (g/dL), Mean ± SD | 3.8 ± 0.5 | 3.8 ± 0.6 | NS |
| AST (IU), Mean ± SD | 24.6 ± 12.5 | 24.6 ± 12.2 | NS |
| ALT (IU), Mean ± SD | 15.2 ± 8.8 | 17.9 ± 18.8 | NS |
| Glucose (mg/dL), Mean ± SD | 107.4 ± 25.3 | 100.7 ± 23.3 | NS |
| CRP (mg/dL), Mean ± SD | 3.3 ± 3.4 | 3.0 ± 3.8 | NS |
| Creatinine (mg/dL), Mean ± SD | 0.8 ± 0.2 | 0.9 ± 0.3 | NS |
SGM slowly growing nontuberculous mycobacteria; RGM rapidly growing nontuberculous mycobacteria, NS not statistically significant (p > 0.05). WBC white blood cell count; AST aspartate transaminase; ALT alanine transaminase; CRP C-reactive protein