Table 4.
Different combinations of the seven lists of HIF potential targets
| Combination | N | In this study | C1 | p.v. | C2 | p.v. | Comments |
|---|---|---|---|---|---|---|---|
| Union of all | 1521 | 1172 | 42 | 0.26 | 145 | 1.2 × 10−38 | - |
| Intersection of all | 2 | 2 | 0 | 1 | 7.5 × 10−2 | Gene RSBN1 in (C2) | |
| Intersection of studies with HIF1α (L1, L2, L4, L5, and L6) | 11 | 10 | 0 | 6 | 5.7 × 10−7 | Genes in (C2): CA9, DARS, GAPDH, PLOD2, RSBN1, and SPRY1 | |
| In 3 lists or more | 144 | 126 | 0 | 61 | 1.2 × 10−52 | - | |
| In 4 lists or more | 60 | 49 | 0 | 30 | 1.5 × 10−30 | - | |
| In 5 lists or more | 28 | 22 | 0 | 15 | 6.4 × 10−17 | Genes in (C2): CA9, DARS, ENO1, GAPDH, GBE1, HK2, INHA, INSIG2, KIAA0195, P4HA1, PLOD2, RSBN1, SPRY1, STC2, WSB1 |
The first column describes the combination of the lists, the second column shows the number of genes in the combination, the third column shows the number of those genes which are included in the input 15,588 genes in our study, the fourth and the fifth columns show the numbers of those genes which are included in C1 and C2, respectively, with their p-values, and the last column shows some comments