Fig. 1.

Representative EEG after PTZ injection. a Representative 10-min EEG from WT mouse shows three clinical epileptic stages after PTZ administration progressing from a healthy baseline (i), to developing epileptic spike trains (ii), and a run of frequent myoclonic seizures as indicated by markers (iii). b Representative 10-min EEG from Shank3B knockout exhibits epileptic spike-trains but has noticeably fewer myoclonic seizures than wildtypes