Table 2.

Retinoblastomas detected in selected infants who underwent screening

Reference	Gestational week		Family history	Laterality and IIRC group at diagnosis	Details
	Birth	Diagnosis
Prenatal screening for retinoblastoma in mutation carriers
Paquette et al.[15]	N/A	37	Yes	Bilateral B/B	US, 2 mm thick tumor
Neriyanuri et al.[16]	34	2 years*	Yes	Unilateral A	None detected at birth (13q - deletion)
Staffieri et al.[17]	38	4/2 weeks*	Yes	Unilateral A	None detected at 1 day
	37	6/3 weeks*	Yes	Unilateral B	None detected at 3 days
	40	-	Yes	None	By 2 years, low penetrance mutation
	36	5/1 weeks*	Yes	Unilateral A	None detected at 2 days
	35	35	Yes	Bilateral B/B	MRI, 6 mm×1.9 mm and 5 mm×1.2 mm tumor
Shah et al.[14]	Term	10 days*	Yes	Bilateral B/A	None detected at 3 days
Soliman et al.[19]	39	Birth	Yes	Bilateral C/B	None detected prenatally
	36	36	Yes	Bilateral B/B	US, detected at 34 weeks
	36	Birth	Yes	Unilateral A	Detected at birth
	37	17/14 weeks*	Yes	Unilateral A	None detected at birth
	36	15/11 weeks*	Yes	Bilateral B/B	None detected at birth
	38	5/3 weeks*	Yes	Bilateral A/A	None detected at birth
Postnatal screening for retinopathy of prematurity
Amino et al.[20]	26	7 weeks/33*	No	Bilateral B/A	Dizygotic twin
	26	7 weeks/33*	No	Bilateral B/B	Dizygotic twin
Picton et al.[21]	32	3 weeks/35*	No	Bilateral	Fetal distress
Self et al.[22]	26	8 weeks/34*	No	Bilateral B/B	Dizygotic twin, in vitro fertilization
Al-Abdi[23]	28	4 weeks/32*	No	Bilateral	Dizygotic twin (c. 635delT)
Abramson et al.[24]	26	12 weeks/38*	No	Unilateral B	Dizygotic twin

*Postnatal/corrected. N/A: Not available, IIRC: International Intraocular Retinoblastoma Classification (Murphree),[25,26] MRI: Magnetic resonance imaging, US: Ultrasound