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. Author manuscript; available in PMC: 2018 Apr 1.
Published in final edited form as: Drugs. 2017 Apr;77(6):615–628. doi: 10.1007/s40265-017-0725-1

Table 1.

Activities of avibactam, vaborbactam and relebactam against various classes of β-lactamases. TBD: To be determined.

TEM/SHV (Class A) CTX-M (Class A) AmpC (Class C) K. pneumoniae carbapenemase (Class A) OXA (Class D) IMP/VIM (Class B)
Avibactam YES YES YES YES YES NO
Vaborbactam YES YES YES YES NO NO
Relebactam YES YES YES YES TBD NO