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. Author manuscript; available in PMC: 2018 Jan 17.
Published in final edited form as: Chem Res Toxicol. 2016 Dec 8;30(1):420–433. doi: 10.1021/acs.chemrestox.6b00386

Table 3.

Levels of AGT in lung and liver in A/J mice treated with NNK. 106

fmol AGT/mg proteinb
Tissue Treatmenta 4 h 96 h
Lung 0 μmol NNK 28 ± 5 33 ± 6
10 μmol NNK 7 ± 2 8 ± 2
Liver 0 μmol NNK 110 ± 30 110 ± 20
10 μmol NNK 0 ± 0 110 ± 30
a

Groups of 30 mice were given i.p. injections NNK (0 or 10 umol) in saline (0.2 mL). Each group was subdivided into 2 groups for sacrifice at 4 or 96 h.

b

Mean of 4 - 13 samples ± SD.