. 2005 Feb;49(2):565–570. doi: 10.1128/AAC.49.2.565-570.2005

TABLE 1.

Synergistic in vitro activity of MC-04,124 combined with LVX against laboratory strains of P. aeruginosa

Strain^a	Genotype	MIC of EPI alone (μg/ml)	LVX MIC (μg/ml) in the presence of the following concentrations of MC-04,124 (μg/ml):								Fold decrease in MIC at 10 μg/ml	Fold decrease in MIC at 20 μg/ml
Strain^a	Genotype	MIC of EPI alone (μg/ml)	0	1.25	2.5	5	10	20	40	80	Fold decrease in MIC at 10 μg/ml	Fold decrease in MIC at 20 μg/ml
PAM1020	PAO1 prototroph	>80	0.125	0.125	0.125	0.125	0.016	0.016	0.008	0.008	8	8
PAM1723	nalB ΔmexCD-oprJ::Gm ΔmexEF-oprN::ΩHg	>80	2	1	1	0.5	0.125	0.031	0.031	0.008	16	64
PAM1738	nfxB ΔmexAB-oprM::Cm ΔmexEF-oprN::ΩHg	>80	2	2	1	0.5	0.125	0.016	0.008	0.008	16	256
PAM1753	nfxC ΔmexAB-oprM::Cm ΔmexCD-oprJ::Gm	>80	2	2	2	1	0.125	0.016	0.008	0.008	16	128
PAM1626	ΔmexAB-oprM::Cm ΔmexCD-oprJ::Gm ΔmexEF-oprN::ΩHg	>80	0.016	0.016	0.008	0.008	0.016	0.008	0.008	0.008	1	2

Source of strains from reference 22.