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. 2017 Apr 24;292(24):9975–9987. doi: 10.1074/jbc.M117.776476

Figure 4.

Figure 4.

Conformational flexibility in IgE-Fc. A, side view of free IgE-Fc (8) showing its acute asymmetric bend. B, front view of free IgE-Fc (90° anti-clockwise rotation from the view shown in A). C, side view of IgE-Fc from the FabXol3 complex, revealing a partially bent conformation. D, front view of IgE-Fc in the FabXol3 complex (90° anti-clockwise rotation from the view shown in C). E, side view of fully extended IgE-Fc captured by an anti-IgE-Fc Fab (aϵFab) (16). F, front view of extended IgE-Fc (90° anti-clockwise rotation from the view shown in E).