TABLE 2.
Strain | ndh allele | Mutation
|
MIC (μg/ml)
|
|||
---|---|---|---|---|---|---|
DNA | Amino acid | INH | ETH | TRC | ||
BCG Pasteur | ndh | Wild type | Wild type | 0.1 | 2.5 | 5 |
mc22402 | ndh-3 | insbp272(a)a | Frameshift | 0.3 | 15 | 15 |
mc22403 | ndh-443 | insbp439(t) | Frameshift | 0.6 | 15 | 10 |
mc22404 | ndh-44 | C604T | R202W | 0.3 | 10 | 10 |
mc22400 | ndh-33 | T716C | L239P | 0.25 | 12.5 | 12.5 |
mc22401 | ndh-38 | T986C | V329A | 0.25 | 10 | 15 |
mc22405 | ndh-55 | A1097G | D366G | 0.3 | 20 | 10 |
insbp272(a) refers to insertion base pair a at position 272.