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(A) Inhibition of cellular HR activity by 1 and optimized analogues of 1 using the DR-GFP assay. Data were collected at 24 h following transfection with the I-SceI expressing plasmid pCBASce. Error bars denote the standard error for three replicates. (B) Inhibition of cellular HR and SSA activity by 9h at 24 h post-transfection. Error bars denote the standard error for three replicates.
