Figure 5.

Applications of cell-to-cell protrusions in intercellular communication A) Image of the BloC-printing device displayed with ruler for scale and colored die for the visualization the channels B) Schematics of chip design with the symmetrical channel networks C) Flexibility of cell trapping with ribbon pattern as an example and body to body cell pairing with red and green cells with enlarged micrograph of cell pairs within dotted line D) Calcein transfer via GJIC in cell pairs with protrusion-to-protrusion and body-to-body pairing methods E) Forward and backwards protrusions generated by the fibroblasts after three hours of trapping¹⁰⁵. Fig 5. Reproduced from Ref 105 with permission from the National Academy of Sciences.