Table 7.
Estimated Overall Contribution of Sequence Type 131 (ST131) to Antimicrobial Resistance Within the SENTRY Collection
Resistance Phenotype | Overall Prevalence, % a | ST131 fraction, % b |
---|---|---|
Ampicillin-sulbactam | 51.9 | 43.2 |
Piperacillin-tazobactam | 8.4 | 42.0 |
Cefotaxime | 12.0 | 52.7 |
Ceftazidime | 7.8 | 52.7 |
Ceftriaxone | 11.2 | 54.0 |
Aztreonam | 9.6 | 54.9 |
Ertapenem | 1.5 | 28.6 |
Imipenem | 3.2 | 33.3 |
Gentamicin | 12.3 | 67.7 |
Tetracycline | 31.4 | 43.4 |
Ciprofloxacin | 29.7 | 70.7 |
Trimethoprim-sulfamethoxazole | 22.5 | 64.9 |
Multidrug resistance (≥ 3 classes) | 17.7 | 65.9 |
aOverall resistance prevalence was imputed for each agent by multiplying the prevalence of resistance to that agent within a given resistance category by the fractional contribution of that resistance category to the total population, then summing these values across the 3 resistance categories.
bST131’s fractional contribution to overall resistance prevalence was imputed for each agent by calculating, for each resistance category, the net contribution of ST131 to resistance within that resistance category, then adjusting for the fractional contribution of that resistance category to the total population, and summing these values across the three resistance categories.