TABLE 1.
Antibiotic | MIC | All strains |
Streptococcus group
|
||||
---|---|---|---|---|---|---|---|
S. mitis (n = 72) | S. anginosus (n = 49) | S. sanguis (n = 21) | S. salivarius (n = 11) | S. bovis (n = 18) | |||
Penicillin | Range | ≤0.03-64 | ≤0.03-64 | ≤0.03-2 | ≤0.03-2 | 0.06-8 | 0.03-2 |
MIC50 | 0.06 | 0.12 | 0.06 | 0.12 | 0.25 | 0.06 | |
MIC90 | 2 | 4 | 0.12 | 0.25 | 1 | 0.25 | |
% S | 71.1 | 55 | 94 | 57 | 64 | 89 | |
% I | 21.3 | 28 | 6 | 43 | 27 | 11 | |
% R | 7.6 | 17 | 0 | 0 | 9 | 0 | |
Erythromycin | Range | ≤0.03-256 | 0.06-256 | ≤0.03-256 | 0.06-256 | 0.06-256 | 0.06-256 |
MIC50 | 0.12 | 0.12 | 0.12 | 1 | 0.06 | 256 | |
MIC90 | 256 | 128 | 256 | 64 | 4 | 256 | |
% S | 52.6 | 50 | 63 | 48 | 73 | 22 | |
% I | 1.8 | 4 | 0 | 0 | 0 | 0 | |
% R | 45.6 | 46 | 37 | 52 | 27 | 78 | |
Clindamycin | Range | ≤0.03-256 | ≤0.03-256 | ≤0.03-128 | ≤0.03-64 | ≤0.03-0.12 | ≤0.03-256 |
MIC50 | 0.06 | 0.06 | 0.06 | 0.06 | 0.06 | 64 | |
MIC90 | 256 | 128 | 128 | 32 | 0.12 | 256 | |
% S | 72.3 | 78 | 69 | 81 | 100 | 28 | |
% I | 0 | 0 | 0 | 0 | 0 | 0 | |
% R | 27.7 | 22 | 31 | 19 | 0 | 72 | |
Telithromycin | Range | ≤0.015-128 | ≤0.015-2 | ≤0.015-1 | ≤0.015-0.25 | ≤0.015-0.06 | ≤0.015-128 |
MIC50 | ≤0.015 | ≤0.015 | ≤0.015 | ≤0.015 | ≤0.015 | 0.12 | |
MIC90 | 0.25 | 0.12 | 0.12 | 0.12 | 0.03 | 64 | |
% S | 95.5 | 99 | 100 | 100 | 100 | 61 | |
% I | 0.5 | 1 | 0 | 0 | 0 | 0 | |
% R | 4 | 0 | 0 | 0 | 0 | 39 |
MIC50, MIC at which 50% of the isolates tested are inhibited; MIC90, MIC at which 90% of the isolates tested are inhibited; % S, percent susceptible; % I, percent intermediate; % R, percent resistant. All MICs are in micrograms per milliliter.