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. 2005 Feb;49(2):820–823. doi: 10.1128/AAC.49.2.820-823.2005

TABLE 1.

MIC50, MIC90, ranges, and susceptibility percentages of the antibiotics tested for different groups of speciesa

Antibiotic MIC All strains Streptococcus group
S. mitis (n = 72) S. anginosus (n = 49) S. sanguis (n = 21) S. salivarius (n = 11) S. bovis (n = 18)
Penicillin Range ≤0.03-64 ≤0.03-64 ≤0.03-2 ≤0.03-2 0.06-8 0.03-2
MIC50 0.06 0.12 0.06 0.12 0.25 0.06
MIC90 2 4 0.12 0.25 1 0.25
% S 71.1 55 94 57 64 89
% I 21.3 28 6 43 27 11
% R 7.6 17 0 0 9 0
Erythromycin Range ≤0.03-256 0.06-256 ≤0.03-256 0.06-256 0.06-256 0.06-256
MIC50 0.12 0.12 0.12 1 0.06 256
MIC90 256 128 256 64 4 256
% S 52.6 50 63 48 73 22
% I 1.8 4 0 0 0 0
% R 45.6 46 37 52 27 78
Clindamycin Range ≤0.03-256 ≤0.03-256 ≤0.03-128 ≤0.03-64 ≤0.03-0.12 ≤0.03-256
MIC50 0.06 0.06 0.06 0.06 0.06 64
MIC90 256 128 128 32 0.12 256
% S 72.3 78 69 81 100 28
% I 0 0 0 0 0 0
% R 27.7 22 31 19 0 72
Telithromycin Range ≤0.015-128 ≤0.015-2 ≤0.015-1 ≤0.015-0.25 ≤0.015-0.06 ≤0.015-128
MIC50 ≤0.015 ≤0.015 ≤0.015 ≤0.015 ≤0.015 0.12
MIC90 0.25 0.12 0.12 0.12 0.03 64
% S 95.5 99 100 100 100 61
% I 0.5 1 0 0 0 0
% R 4 0 0 0 0 39
a

MIC50, MIC at which 50% of the isolates tested are inhibited; MIC90, MIC at which 90% of the isolates tested are inhibited; % S, percent susceptible; % I, percent intermediate; % R, percent resistant. All MICs are in micrograms per milliliter.