Table 1. Two-compartment pharmacokinetics of docetaxel, from Onoue et al. (2016) [ 9, Table 2].
CL: clearance; Q: intercompartmental clearance; V c: volume of central compartment; V p volume of peripheral compartment; CV: coefficient of variation. (*) A CV for V c was unavailable in 9 and has been set arbitrarily to 0.1.
Param | Units | Mean | CV |
---|---|---|---|
CL | L/hour | 32.6 | 0.295 |
Q | L/hour | 5.34 | 0.551 |
V c | L | 5.77 | 0.1* |
V p | L | 11.0 | 0.598 |