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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: J Psychiatr Res. 2017 Feb 24;91:83–89. doi: 10.1016/j.jpsychires.2017.02.023

Table 3.

Prediction of Depressive Episode Onset Across 18-months by 5-HTTLPR and Attention Bias to Emotional, Faces (Sad, Angry, Happy)

Angry Emotion
Logistic Regression Model Summary:
−2LL= 285.61, Model LL= 28.60, McFadden= .09, CoxSnell= .07, Nagelkerke= .13
Predictor b (SE b) 95% CI z p
 Intercept −2.75(0.62) [−3.96, −1.54] −4.46 <.001
 5-HTTLPR 0.02(0.41) [−0.80, 0.83] 0.04 .97
 Angry Bias 0.01(0.004) [−0.0002, 0.01] 1.89 .06
 5-HTTLPR x Angry Bias −0.02(.008) [−0.04, −0.01] −2.91 .004
 MASC 0.01(0.01) [−0.02, 0.04] 0.75 .45
 Past MDD 1.48(0.32) [0.84, 2.11] 4.57 <.001
Sad Emotion
Logistic Regression Model Summary:
−2LL= 288.31, Model LL= 22.10, McFadden= .07, CoxSnell= .05, Nagelkerke= .10
Predictor b (SE b) 95% CI z p
 Intercept −2.59(0.61) [−3.79,−1.39] 0.20 <.001
 5-HTTLPR1 0.30(0.36) [−36.04, −0.39] −2.01 .05
 Sad Bias −0.004(0.003) [−0.01, 0.002] −1.24 .21
 5-HTTLPR x Sad Bias 0.01(0.008) [−0.005, 0.03] 1.31 .19
 MASC 0.008(0.01) [−0.02, 0.04] 0.60 .55
 Past MDD 1.37(0.31) [0.76,1.98] 4.38 <.001
Happy Emotion
Logistic Regression Model Summary:
−2LL= 294.12, Model LL= 20.42, McFadden= .06, CoxSnell= .05, Nagelkerke= .09
Predictor b (SE b) 95% CI z p
 Intercept −2.52(0.60) [−3.70, −1.34] −4.18 <.001
 5-HTTLPR 0.28(0.36) [−0.41, 0.98] 0.80 .43
 Happy Bias −0.0001(0.003) [−0.007, 0.006] −0.03 .97
 5-HTTLPR x Happy Bias 0.009(0.007) [−0.005, 0.02] 1.22 .22
 MASC 0.008(0.01) [−0.02, 0.03] 0.55 .58
 Past MDD 1.30(0.31) [0.70 1.90] 4.23 <.001

Note. MASC =Multidimensional Anxiety Scale for Children; Past MDD= History of clinical depression as measured at the baseline assessment by using a best estimate of parent and child K-SADS interviews.

1

Did not remain significant once removing nonsignificant higher order interaction.