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Cisplatin release in the presence of serum and cytotoxicity against the C26 cells in culture.
| Name | Formulation | % Release after 72 h | IC50 (uM) |
|---|---|---|---|
| C8Chems | Chems:PEG (95:5) | 26% | 5.0 |
| DChems/DPPC | DChems:DPPC:PEG (32:63:5) | 20% | 5.8 |
| C16Chems | Chems:PEG (95:5) | <5% | 79 |
| C18:1Chems | Chems:PEG (95:5) | <5% | >115 |
| DChems | DChems:PEG (95:5) | <5% | 53 |
| HSPC | HSPC:Chol:PEG (51:44:5) | <5% | 260 |
| POPC 51 | POPC:Chol:PEG (51:44:5) | 14% | 130 |
| POPC 80 | POPC:Chol:PEG (80:15:5) | 37% | 5.9 |
