The proportion of Aβ positivity and topographical distribution of Aβ in frontotemporal dementia (FTD) syndromes and age-matched controls. The proportion of patients that demonstrate no Aβ deposition (A0), Aβ in the frontal-temporal cortices (A1), additional Aβ in the basal ganglia (A2), and additional Aβ in the substantia nigra (A3) is shown in patients with behavioral variant frontotemporal dementia (bvFTD), semantic variant primary progressive aphasia (sv-PPA), non-fluent variant primary progressive aphasia (nfv-PPA), and age-matched controls. Table inset demonstrates the percentage of cases with any Aβ deposition by age. As only one nfv-PPA and one control demonstrated an A3 distribution, these have been combined with the A2 group in the present figure.