Fig 4. Large-scale modulation of the Min oscillator by reducing MinE’s membrane affinity.

Biochemical alterations, such as single mutations, in MinE’s membrane targeting sequence cause a marked reduction in the lower limit of the length scale of Min protein patterns along with unusual dynamic modes in cell-like geometry. Thus, the Min oscillator is both highly versatile and sensitive to biochemical changes. Scale Bars: 50 μm (left) and 5 μm (right). P_i: inorganic phosphate. Units and values on graphs are left out for simplicity (see Figs 1 and 3 for data).