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. 2017 Jun 6;12:4225–4239. doi: 10.2147/IJN.S130861

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© 2017 Chen et al. This work is published and licensed by Dove Medical Press Limited

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Observation of lysosomal disruption of MCF-7 cells treated with PBS, Cypate/DOX-L, and Cypate/DOX-BTSL at the Cypate concentrations of 0.5, 1, and 2 μg/mL with or without laser irradiation using AO staining. Scale bars represent 50 μm and magnification ×12.6.

Abbreviations: PBS, phosphate-buffered saline; DOX, doxorubicin; L, (NH₄)₂SO₄ liposomes; BTSL, bubble-generating thermosensitive liposomes (NH₄HCO₃); AO, acridine orange.