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. 2017 Jun 6;12:4269–4283. doi: 10.2147/IJN.S124264

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© 2017 Zhou et al. This work is published and licensed by Dove Medical Press Limited

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Ultrastructure observation of oral buccal tissues through injection with 5% dextrose solution, Fungizone (AmB+DOC), AmB/MPP micelles, and MPP blank micelles after dosing for 30 days under transmission electron microscope.

Notes: (A) Epithelial surface layer of the oral buccal tissues (10,000×); (B) epithelial middle layer containing prickle cells (10,000×); (C) basement membrane (30,000×, orange arrows pointed to the disappeared parts in the basement membrane of the AMB+DOC group); (D) desmosome junctions between epithelial cells (30,000×, orange arrows pointed to the residual desmosome junctions in AmB+DOC group).

Abbreviations: AmB, amphotericin B; DOC, sodium deoxycholate; MPP, monomethoxy poly(ethylene glycol)-poly(epsilon-caprolactone)-graft-polyethylenimine.