Table 1.
Composition of different buccal tablets
| Composition | Content (mg)
|
||
|---|---|---|---|
| T1 | T2 | T3 | |
| MPC85 | 27.43 | 27.43 | 27.43 |
| HPMC K4M | 20.50 | 20.50 | 20.50 |
| Corn starch | 58.36 | 49.18 | 49.18 |
| Anhydrous lactose | 5.57 | 5.57 | 5.57 |
| Magnesium stearate | 1.32 | 1.32 | 1.32 |
| AmB | 1.00 | 1.00 | – |
| MPEG-PCL-g-PEI | – | 10.00 | – |
| AmB/MPEG-PCL-g-PEI | – | – | 11.00 |
| DOC | 0.82 | – | – |
Note: T1, AmB+DOC; T2, AmB+MPP; T3, AmB/MPP micelles.
Abbreviations: AmB, amphotericin B; MPEG-PCL-g-PEI, monomethoxy poly (ethylene glycol)-poly(epsilon-caprolactone)-graft-polyethylenimine; DOC, sodium deoxycholate; MPP, monomethoxy poly(ethylene glycol)-poly(epsilon-caprolactone)-graft-polyethylenimine.