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. 2017 Jun 2;12:4195–4208. doi: 10.2147/IJN.S132190

Figure 8.

Figure 8

Effect of PDAPEI/miR-221/222 on the expression of nerve growth factor (NGF) and myelin basic protein (MBP) in SCs in vitro.

Notes: (A) NGF and MBP expression determined by western-blot analysis and (B) RT-PCR analysis of NGF and MBP miRNA expression. βP<0.05, the blank group versus miR-221/222 group; δP<0.05, the NC group versus miR-221/222 group; #P<0.05, ##P<0.01, miR-221/222+ group versus the blank group; ϕP<0.05, ϕϕP<0.01, miR-221/222+ group versus the NC group; **P<0.01, ***P<0.001, miR-221/222+ group versus miR-221/222 group.

Abbreviations: MBP, myelin basic protein; NGF, nerve growth factor; PDAPEI, PEI (1.8 kDa, branched) derivative with 2,6-pyridinedicarboxaldehyde (PDA) linkage; PEI, polyethylenimine; NC, negative control; SCs, Schwann cells.