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. 2017 Jun 2;12:4195–4208. doi: 10.2147/IJN.S132190

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© 2017 Song et al. This work is published and licensed by Dove Medical Press Limited

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Effect of PDAPEI/miR-221/222 on the expression of nerve growth factor (NGF) and myelin basic protein (MBP) in SCs in vitro.

Notes: (A) NGF and MBP expression determined by western-blot analysis and (B) RT-PCR analysis of NGF and MBP miRNA expression. ^βP<0.05, the blank group versus miR-221/222⁻ group; ^δP<0.05, the NC group versus miR-221/222⁻ group; ^#P<0.05, ^##P<0.01, miR-221/222⁺ group versus the blank group; ^ϕP<0.05, ^ϕϕP<0.01, miR-221/222⁺ group versus the NC group; **P<0.01, ***P<0.001, miR-221/222⁺ group versus miR-221/222⁻ group.

Abbreviations: MBP, myelin basic protein; NGF, nerve growth factor; PDAPEI, PEI (1.8 kDa, branched) derivative with 2,6-pyridinedicarboxaldehyde (PDA) linkage; PEI, polyethylenimine; NC, negative control; SCs, Schwann cells.