Table 1.

Characteristics of lean controls and obese patients before and after surgery

	Groups				P Values
	LEAN	LAGB	RYGB	SG	ap	bp
n (M/F)	8 (4/4)	9 (2/7)	21 (4/17)	11 (2/9)
Age (y)	31.3 ± 4.7	43.4 ± 3.4	43.1 ± 2.4	39.9 ± 2.9	.019	.750
Postop period (mo)	NA	8.8 ± .9	6.6 ± .4	6.0 ± .0	NA	.003
Wt (kg)
Pre	61.9 ± 3.0	123.8 ± 10.5	127.5 ± 5.9	114.0 ± 7.1	.000	.000
Post		105.2 ± 9.5*	94.6 ± 5.1*	94.7 ± 5.6†
EWL (%)	NA	29.1 ± 4.5	40.4 ± 3.2	38.6 ± 4.4	NA	.085
BMI (kg/m2)
Pre	21.8 ± .7	42.5 ± 2.7	47.8 ± 1.7	46.4 ± 1.7	.000	.000
Post		36.1 ± 2.5*	35.3 ± 1.4*	36.0 ± 1.3*
Leptin-F (ng/mL)
Pre	4.5 ± 1.8	40.2 ± 4.9	42.4 ± 2.9	67.9 ± 6.2	.000	.002
Post		25.6 ± 3.6*	18.6 ± 1.8*	29.2 ± 7.2*
Glucose-F (mg/dL)
Pre	88.5 ± 2.2	109.2 ± 5.2	117.7 ± 11.6	100.4 ± 7.5	.006	.875
Post		94.5 ± 2.6*	95.5 ± 4.2*	79.0 ± 2.3‡
Glucose-AUC
Pre	168 ± 5	231 ± 22	261 ± 28	239 ± 24	.000	.436
Post		174 ± 6†	185 ± 15*	157 ± 6†
Insulin-F (μIU/mL)
Pre	4.5 ± .9	19.7 ± 2.9	18.3 ± 2.5	23.0 ± 3.8	.023	.539
Post		10.6 ± 1.3†	8.2 ± 1.3*	9 ± 2.3†
Insulin-AUC
Pre	34 ± 5	134 ± 17	112 ± 15	162 ± 29	.000	.631
Post		72 ± 8*	66 ± 13†	72 ± 12†
HOMA-IR
Pre	1.0 ± .21	5.4 ± .8	5.5 ± .9	5.0 ± 1.2	.000	.909
Post		2.5 ± .3†	1.9 ± .3*	1.7 ± .5†
Apo A-IV F (μg/mL)
Pre	443 ± 49.6	483 ± 68	481 ± 57	690 ± 131	.694	.109
Post		493 ± 67	506 ± 53	570 ± 130
Apo A-IV AUC (× 103)
Pre	53.6 ± 5.6	61.8 ± 7.6	59 ± 5.7	76.2 ± 14.7	.474	.569
Post		61.8 ± 7.9	61.3 ± 6.6	65.6 ± 11.5
PYY-F (pg/mL)
Pre	91 ± 26	111 ± 22	124 ± 32	64 ± 22	.442	.302
Post		101 ± 16	127 ± 19	71 ± 20
PYY-AUC
Pre	271 ± 46	332 ± 69	317 ± 56	182 ± 36	.422	.003
Post		403 ± 100	675 ± 102*	273 ± 52‡

F = fasting values; AUC = area under the curve from 0–120 minutes.

Paired analyses before and after surgery are indicated as follows:

^aP = Comparison between lean and obese patients combined before surgery.

^bP = Analysis of the pre to postsurgery change between the different surgical groups.

^*P < .001

^†P < .01

^‡P < .05.