. 2017 Jun 3;15:525–540. doi: 10.1016/j.nicl.2017.06.005

Table 7.

Between-group differences in brain activations during humor processing.

Contrast	Healthy controls > Schizophrenia outpatients
Contrast	side/brain region	BA	k	MNI (x; y; z)	Pseudo-t
1. Incongruity detection (ABS vs NEU)	R posterior Superior Temporal Gyrus	41	40	42; − 40; 11	3.78
2. Incongruity resolution and elaboration (FUN vs ABS) & Comprehension rating*	L dorsomedial Middle Frontal Gyrus/Superior Frontal Gyrus	8/9	21	− 9; 38; 38	4.34
	L dorsomedial Middle Frontal Gyrus/Superior Frontal Gyrus	8/9	40*	− 6; 38; 38*	4.13*
3. Complete humor processing (FUN vs NEU) & Funniness rating*	L > R interhemispheric dorsal Anterior Cingulate Cortex	24	35	− 6; 2; 26	3.75
	L > R interhemispheric dorsal Anterior Cingulate Cortex	24	10*	− 3; − 1; 29*	2.98*

List of brain regions revealed by between-group contrasts during humor comprehension process and with comprehensibility and funniness ratings analyzed as parametric modulators (*). Statistical analysis utilized a non-parametric whole-brain voxel-wise Pseudo-t-test. Localizations are reported as local maximum threshold with k ≥ 10 voxels extent threshold and with False Discovery Rate (FDR) correction at alpha = 0.0500, or uncorrected at alpha = 0.0010. L – left hemisphere; R – right hemisphere; BA – Brodmann's area; k – number of voxels in analyzed cluster size; MNI - Montreal Neurological Institute coordinates.