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. 2017 May 18;100(6):954–959. doi: 10.1016/j.ajhg.2017.04.013

Figure 3.

Figure 3

Heatmap of the SMR Results for 32 DNA Methylation Sites Associated with Crohn Disease across 38 GWAS Datasets

Each square in the heatmap represents the t-statistic (b_SMR/se_SMR) of the GWAS trait (columns) for a DNA methylation site (row; n = 32) associated with Crohn disease. Only phenotypes (n = 38) tested against at least 20,000 DNA methylation sites were included in this comparison. SMR p < 1.38 × 10−6 and HEIDI p > 0.05.