Figure 2.

Comparison of the SDL dataset with other genome-wide screens. (A) Overlap between the “hub” SDL networks of CDC28 and the kinases SLT2, BCK1, ELM1, and PHO85. Data were obtained from Sharifpoor et al. (2012). (B) Overlap between the SDL screen and previously identified genes with a negative genetic relationship with CDC28. Data were obtained from BioGRID. (C and D) Overlap between the SDL screen and the SGA screen described in Zimmermann et al. (2011). (E) Overlap between the SDL screen and previously identified genes that cause dosage lethality of cdc28 mutants (data from BioGRID). SDL, synthetic dosage lethality; SGA, synthetic genetic array.