Table 2. Summary of phenotypes for HEM25 SLC25 family genetics interactors.

	Growth						Heme Level (% WT)		ETC Complex Stability
Strain	Glycine as N Source	hem 25Δ	Dextrose as C Source	hem 25Δ	Lactate as C Source	hem25Δ	Heme Content	hem25Δ	I	hem25Δ	II	hem25Δ	III	hem25Δ	IV	hem25Δ	V	hem25Δ
Wild type	++++a		++++		+++		100		+++		+++		+++		+++		+++
hem25Δ	+++		++++		+++		35		+++		++		++		++		+++
flx1Δ	+++	++	++++	++++	—b	—	49	10	++++	+	+++	+	++++	+	++++	++	+++	+++
mtm1Δ	+++	++	++	+c	—	—	22	19
ort1Δ	+++	+	++++	—	—d	—	42	5
sfc1Δ	++++	+++	++++	++++	—b	—b	40	8
pet8Δ	++	+	++++	++b	—	—	38	8
aac3Δ	+++++	+++	+++++	++++	++++	—	150	57

^aRelative level.

^bAlleviated by glycine and 5-Ala.

^cAlleviated by 5-Ala.

^dAlleviated by glycine.