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. 2017 Jun 16;7:3733. doi: 10.1038/s41598-017-03838-y

Table 1.

pKa values determined for analogs of sialyllactose.

ACD/Lab method Predicted pKa value
α2,3-sialyllactose 1.9 (±0.7)
α2,6-sialyllactose 2.0 (±0.7)
Conventional CE method Absolute pK a value
α2,3-sialyllactose 1.8 (±0.1)
α2,6-sialyllactose 1.8 (±0.1)
IS-CE method ( N  = 2) Relative pK a value
3.4·10−2