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. 2017 Jun 16;7:3664. doi: 10.1038/s41598-017-03986-1

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Case study of lncRNA MALAT1. The four chord graphs show the results of PLPIHS (A), PRINCE (B), RWR (C) and LPIHN (D) respectively. The biggest baby blue node represents lncRNA MALAT1 and the other nodes are related proteins, red lines denotes wrong prediction while green lines are correct prediction and the violet lines means the interactions between proteins.