Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jun 16;7:3652. doi: 10.1038/s41598-017-03899-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Gene and protein expressions of Wnt/β-catenin pathway related factors in BMSCs after osteogenic induction for 12 h (left side of Figure 5) and 24 h (right side). (a) Gene expressions of β-catenin and cyclinD1 by real-time PCR. Both genes were signifcantly elevated in group A (Ad-hApN-EGFP). *P < 0.05. (b) Protein expressions of β-catenin and cyclinD1 by western blotting. The two genes were up-regulated in group A both in cytoplasm and nucleus, and more β-catenin translocated into nucleus. (c) Immunofluorescence staining of BMSCs. Nucleus was stained with DAPI (blue arrow). The β-catenin (white arrow) expressed in both cytoplasm and nucleus and the fluorescent density and intensity were higher in group A.