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. 2017 Jun 16;7:3713. doi: 10.1038/s41598-017-03450-0

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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From left to right: BOLD images, TTP maps, histogram of TTP distribution and histology (10X). One control (top) is compared to one case with abnormal placental pathology (bottom). Yellow dashes in A and E outline the placenta. For healthy subjects, TTP values were short and placental histology was normal. For pathological cases, TTP values were longer and less uniform (blue regions in (F) and blue box in (G)). Arrows in H point to avascular villi and the star identifies chorangiosis.