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. 2017 Jun 16;7:3713. doi: 10.1038/s41598-017-03450-0

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Illustrations of segmentation volumes and of mean time-to-plateau (TTP). (A) placenta for the discordant twin pair with indication of ROI segmentation used for the average TTP calculation. (B) 3D view of segmented fetal brains and livers in the corresponding discordant twin pair (red points in (C–E) below). (C–E) Brain volume, liver volume and birth weight respectively as a function of the average TTP. The brain and liver volume were measured at the time of the scan. Twin pairs are connected by solid line, and are assigned same color. Hollow circles denotes fetuses that proved to be SGA at birth.