Table 3.
Differences in Demographic and Clinical Characteristics Among the Evening Fatigue Latent Classes (n=582)
| Characteristic | Moderate LFS score (0) N=116 (20.0%) |
High LFS score (1) N=127 (21.8%) |
Very High LFS score (2) N=339 (58.2%) |
Statistics |
|---|---|---|---|---|
|
| ||||
| Mean (SD) | Mean (SD) | Mean (SD) | ||
|
| ||||
| Age (years) | 59.7 (11.7) | 57.2 (12.2) | 56.3 (11.7) | F=3.35, p=.036 0 > 2 |
|
| ||||
| Education (years) | 16.3 (3.3) | 15.9 (2.7) | 16.6 (3.0) | F=2.66, p=.071 |
|
| ||||
| Body mass index (kg/m2) | 25.5 (5.1) | 26.6 (6.0) | 26.6 (6.0) | F=1.55, p=.212 |
|
| ||||
| Karnofsky Performance Status score | 85.3 (10.9) | 80.7 (12.1) | 79.1 (11.8) | F=11.06, p<.0001 0 >1 and 2 |
|
| ||||
| Self-administered Comorbidity Questionnaire score | 4.8 (2.8) | 5.8 (3.0) | 5.8 (3.1) | F=5.18, p<.006 0 < 1 and 2 |
|
| ||||
| Time since diagnosis (years) | 2.0 (4.2) | 2.7 (5.4) | 2.5 (4.1) | F=0.90, p=.405 |
|
| ||||
| Number of prior cancer treatments | 1.8 (1.5) | 1.8 (1.6) | 2.0 (1.6) | F=1.02, p=.360 |
|
| ||||
| Number of metastatic sites including lymph node involvement a | 1.4 (1.4) | 1.4 (1.3) | 1.3 (1.3) | F=0.59, p=.553 |
|
| ||||
| Number of metastatic sites excluding lymph node involvement | 1.0 (1.2) | 0.9 (1.2) | 0.9 (1.1) | F=0.42, p=.660 |
|
| ||||
| Hemoglobin | 11.9 (1.4) | 11.6 (1.2) | 11.7 (1.4) | F=1.03, p=.357 |
|
| ||||
| Hematocrit | 35.4 (4.1) | 34.7 (3.6) | 34.8 (4.2) | F=0.96, p=.382 |
|
| ||||
| % | % | % | ||
|
| ||||
| Gender (% female) | 70.7 | 78.7 | 83.8 | Χ2=9.45, p=.009 0<2 |
|
| ||||
| Self-reported ethnicity | ||||
| White | 69.6 | 62.3 | 77.5 | Χ2=11.00, p=.004 |
| Non-white | 30.4 | 37.7 | 22.5 | 1<2 |
|
| ||||
| Married or partnered (% yes) | 70.2 | 65.9 | 67.3 | Χ2=0.53, p=.766 |
|
| ||||
| Lives alone (% yes) | 17.5 | 19.8 | 20.9 | Χ2=0.60, p=.741 |
|
| ||||
| Currently employed (% yes) | 33 | 33.3 | 35.8 | Χ2=0.42 p=.809 |
|
| ||||
| Annual household income | ||||
| Less than $30,000 | 20.6 | 18.6 | 18 | KW, p=.140 |
| $30,000 to $70,000 | 25.5 | 22.1 | 16.7 | |
| $70,000 to $100,000 | 17.6 | 15 | 17.6 | |
| Greater than $100,000 | 36.3 | 44.2 | 47.7 | |
|
| ||||
| Child care responsibilities (% yes) | 14.9 | 20.8 | 27.3 | Χ2=7.82, p=.020 0<2 |
|
| ||||
| Elder care responsibilities (% yes) | 8.4 | 9.2 | 8.8 | Χ2=0.05, p=.976 |
|
| ||||
| Exercise on a regular basis (% yes) | 72.4 | 72.2 | 69.1 | Χ2=0.68, p=.712 |
|
| ||||
| Cancer diagnosis | Χ2=28.90, p<.0001 | |||
| Breast cancer | 31 | 39.4 | 48.4 | 0<2 |
| Gastrointestinal cancer | 41.4 | 22 | 23.3 | 0>1 and 2 |
| Gynecological cancer | 17.2 | 21.3 | 21.2 | n/s |
| Lung cancer | 10.3 | 17.3 | 7.1 | 1>2 |
|
| ||||
| Prior cancer treatment | Χ2=17.57, p=.007 | |||
| No prior treatment | 20.9 | 25 | 13.7 | 1>2 |
| Only surgery, CTX, or RT | 33 | 37.9 | 45.2 | n/s |
| Surgery and CTX, or surgery and RT, or CTX and RT | 32.2 | 20.2 | 21.4 | n/s |
| Surgery and CTX and RT | 13.9 | 16.9 | 19.6 | n/s |
|
| ||||
| Metastatic sites | ||||
| No metastasis | 28.4 | 26.2 | 35.6 | Χ2=6.32, p=.388 |
| Only lymph node metastasis | 21.6 | 23 | 19.6 | |
| Only metastatic disease in other sites | 23.3 | 27 | 19.6 | |
| Metastatic disease in lymph nodes and other sites | 26.7 | 23.8 | 25.2 | |
|
| ||||
| Cycle length | ||||
| 14 day cycle | 47.4 | 30.7 | 33.6 | Χ2=11.15, p=.084 |
| 21 day cycle | 44 | 58.3 | 58.4 | |
| 28 day cycle | 8.6 | 11 | 7.7 | |
| >28 day cycle | 0 | 0 | 0.3 | |
a
Total number of metastatic sites evaluated was 9.
Abbreviations: CTX = chemotherapy, kg = kilograms, KW = Kruskal Wallis, m2 = meters squared, RT = radiation therapy, SD = standard deviation