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Study Design Schema. All subjects (n=13) were scanned in the “unpaired” condition prior to pairing (“Timepoint 1”). Six of these subjects (“Experimental group”) were paired while age-matched controls remained in the unpaired condition, and all underwent a second scan 4-9 weeks later (“Timepoint 2”). Finally, the Control group was paired and PET scanned 4-9 weeks post-pairing.
