Table 2.

Change from baseline for outcomes of social cognitive function

		Oxytocin			Placebo
Outcome Variablea	Time Point (wks)	N	LS Mean (SE)	P-Valueb Diff>0	N	LS Mean (SE)	P-Valueb Diff>0	P-Valuec Trt Diff
Eyes Test total	6	27	−0.48 (0.59)	0.422	27	−1.09 (0.59)	0.070	0.472
	12	26	−0.82 (0.67)	0.227	27	0.17 (0.66)	0.798	0.302
ER-40 total	6	28	1.39 (0.55)	0.014	29	0.83 (0.54)	0.129	0.475
	12	26	0.14 (0.50)	0.782	29	0.93 (0.48)	0.058	0.270
Brüne-A total	6	28	3.28 (1.22)	0.010	28	4.32 (1.19)	0.001	0.552
	12	26	4.52 (1.41)	0.002	29	5.97 (1.36)	0.000	0.469
AIHQ blame bias	6	27	0.05 (0.56)	0.926	29	0.34 (0.53)	0.523	0.712
	12	25	−0.66 (0.54)	0.228	29	−0.53 (0.51)	0.308	0.860
Trustworthiness task -	6	27	0.22 (1.63)	0.894	28	1.13 (1.58)	0.479	0.694
untrustworthy subscale	12	25	0.86 (1.59)	0.591	29	0.24 (1.50)	0.875	0.779
Trustworthiness task -	6	27	1.22 (0.93)	0.194	28	−0.55 (0.90)	0.546	0.183
trustworthy subscale	12	25	−0.73 (1.02)	0.479	29	−0.29 (0.96)	0.761	0.760

Abbreviations: LS, least squares; ER-40, Emotion Recognition-40 task; AIHQ, Ambiguous Intentions Hostility Questionnaire

^aModels adjusted for baseline value and age in addition to treatment group

^bTest for within-group change

^cTest for between-group change